Thrombolysis for acute stroke in the United Kingdom | Zendy

Richard I. Lindley | Zendy

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Thrombolysis for acute stroke in the United Kingdom

Author(s) -

Richard I. Lindley

Publication year - 2002

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/31.suppl_3.28

Subject(s) - thrombolysis , medicine , ischaemic stroke , stroke (engine) , acute stroke , randomized controlled trial , emergency medicine , intensive care medicine , tissue plasminogen activator , ischemia , myocardial infarction , mechanical engineering , engineering

The publication of the National Institute of Neurological Disorders and Stroke trial of thrombolysis has not led to the widespread implementation of alteplase for acute ischaemic stroke in the United Kingdom. However, the Cochrane systematic review of thrombolysis for acute ischaemic stroke suggests that alteplase is the most promising treatment for acute ischaemic stroke. Successful implementation of thrombolysis in the United Kingdom will depend on continued investment in acute stroke services, attention to the known barriers to treatment, further data from randomized controlled trials and the licensing of alteplase for this indication.

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