Review. Carnosine: physiological properties and therapeutic potential | Zendy

Salah Gariballa | Zendy

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Review. Carnosine: physiological properties and therapeutic potential

Author(s) -

Salah Gariballa

Publication year - 2000

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/29.3.207

Subject(s) - carnosine , medicine , antioxidant , neurotransmitter systems , pharmacology , neuroscience , immune system , biochemistry , chemistry , biology , immunology , dopamine

Carnosine and related dipeptides are naturally-occurring histidine-containing compounds. They are found in several tissues, particularly in skeletal muscle. Since carnosine was discovered in Russia in 1900, there have been many theories about its biological functions, but none has been proved beyond reasonable doubt [1, 2]. However, this compound is reported to possess antioxidant, buffering, immune-enhancing and neurotransmitter actions. The aim of this review is to discuss carnosine’s properties, functions and therapeutic potential with special reference to its antioxidant activity.

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