CYP2D6, NAT2 and CYP2EI genetic polymorphisms in nonagenarians | Zendy

José A. G. Agúndez | Zendy; I.J. Posada Rodriguez | Zendy; Manuela Olivera | Zendy; José M. Ladero | Zendy; María del Mar Ballesteros García | Zendy; JosepMaría Ribera | Zendy; Julio Benítez | Zendy

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CYP2D6, NAT2 and CYP2EI genetic polymorphisms in nonagenarians

Author(s) -

José A. G. Agúndez,

I.J. Posada Rodriguez,

Manuela Olivera,

José M. Ladero,

María del Mar Ballesteros García,

JosepMaría Ribera,

Julio Benítez

Publication year - 1997

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/26.2.147

Subject(s) - genotype , cyp2d6 , genetics , allele , longevity , biology , polymorphism (computer science) , medicine , gene , physiology

enzymatic polymorphisms affecting the metabolic disposition of xenobiotics may modulate the rate of activation or deactivation of carcinogens and other toxic environmental chemicals. Hence, these polymorphisms may influence the risk of suffering some types of cancer and other degenerative diseases that are incompatible with extreme longevity.

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