The “Virtual Digital Twins” Concept in Precision Nutrition | Zendy

Kalliopi Gkouskou | Zendy; Ioannis Vlastos | Zendy; Πέτρος Καρκαλούσος | Zendy; Dimitrios Chaniotis | Zendy; Despina Sanoudou | Zendy; Aristides G. Eliopoulos | Zendy

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The “Virtual Digital Twins” Concept in Precision Nutrition

Author(s) -

Kalliopi Gkouskou,

Ioannis Vlastos,

Πέτρος Καρκαλούσος,

Dimitrios Chaniotis,

Despina Sanoudou,

Aristides G. Eliopoulos

Publication year - 2020

Publication title -

advances in nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.362

H-Index - 90

eISSN - 2156-5376

pISSN - 2161-8313

DOI - 10.1093/advances/nmaa089

Subject(s) - psychological intervention , pillar , precision medicine , medicine , psychology , data science , computer science , psychiatry , engineering , structural engineering , pathology

Nutritional and lifestyle changes remain at the core of healthy aging and disease prevention. Accumulating evidence underscores the impact of genetic, metabolic, and host gut microbial factors on individual responses to nutrients, paving the way for the stratification of nutritional guidelines. However, technological advances that incorporate biological, nutritional, lifestyle, and health data at an unprecedented scale and depth conceptualize a future where preventative dietary interventions will exceed stratification and will be highly individualized. We herein discuss how genetic information combined with longitudinal metabolomic, immune, behavioral, and gut microbial parameters, and bioclinical variables could define a digital replica of oneself, a "virtual digital twin," which could serve to guide nutrition in a personalized manner. Such a model may revolutionize the management of obesity and its comorbidities, and provide a pillar for healthy aging.

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