Discovery and multi-parametric optimization of a high-affinity antibody against interleukin-25 with neutralizing activity in a mouse model of skin inflammation
Author(s) -
Ruth E. Bone,
Brian J. Fennell,
Amy Tam,
Richard Sheldon,
Karl Nocka,
Sreeja Varghese,
Chew Shun Chang,
Heike C. Hawerkamp,
Aoife Yeow,
Sean P. Saunders,
Emily Hams,
Patrick Walsh,
Orla Cunningham,
Padraic G. Fallon
Publication year - 2022
Publication title -
antibody therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.579
H-Index - 5
ISSN - 2516-4236
DOI - 10.1093/abt/tbac022
Subject(s) - inflammation , antibody , in vivo , immunology , potency , cytokine , neutralizing antibody , in vitro , tumor necrosis factor alpha , biology , medicine , pharmacology , biochemistry , microbiology and biotechnology
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