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A novel IgG Fc by computer-aided design enhances heavy-chain heterodimerization in bi- or trispecific antibodies
Author(s) -
Bo Wang,
Jun Lin,
Matthew R. Hoag,
Meredith S. Wright,
Mingjun Ma,
Wenyan Cai,
Sachith Gallolu Kankanamalage,
Yue Liu
Publication year - 2022
Publication title -
antibody therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.579
H-Index - 5
ISSN - 2516-4236
DOI - 10.1093/abt/tbac019
Subject(s) - bispecific antibody , antibody , cd20 , cd3 , fragment crystallizable region , chemistry , computational biology , monoclonal antibody , biology , antigen , immunology , cd8

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