Identification of neuropeptide Y-like conopeptides from the venom of &lt;italic&gt;Conus betulinus&lt;/italic&gt; | Zendy

Xuechen Wu | Zendy; XiaoXia Shao | Zendy; ZhanYun Guo | Zendy; ChengWu Chi | Zendy

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Identification of neuropeptide Y-like conopeptides from the venom of <italic>Conus betulinus</italic>

Author(s) -

Xuechen Wu,

XiaoXia Shao,

ZhanYun Guo,

ChengWu Chi

Publication year - 2010

Publication title -

acta biochimica et biophysica sinica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.771

H-Index - 57

eISSN - 1745-7270

pISSN - 1672-9145

DOI - 10.1093/abbs/gmq042

Subject(s) - venom , neuropeptide , neuropeptide y receptor , biology , invertebrate , zoology , biochemistry , fishery , receptor

Neuropeptide Y (NPY) is a ubiquitous endocrine neuropeptide found in vertebrate and invertebrate. In our present work, two NPY-like exocrine conopeptides (designated as cono-NPYs) were first identified in the venom of cone snails. Both cono-NPYs showed sequence characteristics of invertebrate NPYs, suggesting that some exocrine venom peptides are probably evolved from the preexisting endocrine peptides during the evolution of cone snails.

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