Open AccessMesenchymal Stem Cells Home to Sites of Injury and Inflammation
Author(s) -
Kristine C. Rustad,
Geoffrey C. Gurtner
Publication year - 2012
Publication title -
advances in wound care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 24
eISSN - 2162-1934
pISSN - 2162-1918
DOI - 10.1089/wound.2011.0314
Subject(s) - homing (biology) , mesenchymal stem cell , medicine , wound healing , stem cell , inflammation , transplantation , regeneration (biology) , pathology , bioinformatics , immunology , surgery , biology , microbiology and biotechnology , ecology
Mesenchymal stem cells (MSCs) have shown significant therapeutic potential in preclinical animal models of wound healing. However, the translation of MSC-based therapeutics to clinical practice has been delayed by questions including the mechanisms of MSC homing, engraftment, and ultimate function.
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