Open AccessCollagen Organization Critical Role in Wound Contraction
Author(s) -
H. Paul Ehrlich,
Thomas K. Hunt
Publication year - 2012
Publication title -
advances in wound care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.864
H-Index - 24
eISSN - 2162-1934
pISSN - 2162-1918
DOI - 10.1089/wound.2011.0311
Subject(s) - myofibroblast , fibroblast , contraction (grammar) , myosin , wound healing , microbiology and biotechnology , chemistry , granulation tissue , biophysics , type i collagen , actin , anatomy , pathology , in vitro , biology , biochemistry , medicine , immunology , fibrosis , endocrinology
Open wound closure by wound contraction produces a healed defect made up mostly of dermis. Generating thicker collagen fibers condenses granulation tissue, which pulls surrounding skin into the defect.
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