Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats | Zendy

Kuo Zhang | Zendy; YiDa Tang | Zendy; Youhua Zhang | Zendy; Kaie Ojamaa | Zendy; Ying Li | Zendy; Amandeep S. Saini | Zendy; Maria Alícia Carrillo-Sepúlveda | Zendy; Viswanathan Rajagopalan | Zendy; A. Martin Gerdes | Zendy

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Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats

Author(s) -

Kuo Zhang,

YiDa Tang,

Youhua Zhang,

Kaie Ojamaa,

Ying Li,

Amandeep S. Saini,

Maria Alícia Carrillo-Sepúlveda,

Viswanathan Rajagopalan,

A. Martin Gerdes

Publication year - 2018

Publication title -

thyroid

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.918

H-Index - 142

eISSN - 1557-9077

pISSN - 1050-7256

DOI - 10.1089/thy.2017.0544

Subject(s) - medicine , metoprolol , myocardial infarction , triiodothyronine , cardiology , contractility , ligation , pathophysiology , endocrinology , hormone

Beta blockers are standard therapy for myocardial infarction (MI). Preclinical studies have shown efficacy and safety of thyroid hormone (TH) treatment of cardiovascular disorders. Since THs interact with the sympathoadrenergic system, this study aimed to compare triiodothyronine (T3) and metoprolol (Met) in the treatment of rats with MI on pathophysiology and TH-adrenergic signaling.

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