Thyroglobulin as a Functional Biomarker of Iodine Status in a Cohort Study of Pregnant Women in the United Kingdom | Zendy

Sarah C. Bath | Zendy; Victor J.M. Pop | Zendy; Victoria L. Furmidge-Owen | Zendy; Maarten A.C. Broeren | Zendy; Margaret P. Rayman | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Thyroglobulin as a Functional Biomarker of Iodine Status in a Cohort Study of Pregnant Women in the United Kingdom

Author(s) -

Sarah C. Bath,

Victor J.M. Pop,

Victoria L. Furmidge-Owen,

Maarten A.C. Broeren,

Margaret P. Rayman

Publication year - 2016

Publication title -

thyroid

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.918

H-Index - 142

eISSN - 1557-9077

pISSN - 1050-7256

DOI - 10.1089/thy.2016.0322

Subject(s) - biomarker , medicine , thyroglobulin , cohort , cohort study , pregnancy , iodine , obstetrics , environmental health , thyroid , biology , chemistry , genetics , organic chemistry

Though iodine deficiency in pregnancy is a matter of public-health concern, a functional measure of iodine status is lacking. The thyroid-specific protein thyroglobulin (Tg), which reflects thyroid size, has shown promise as a functional measure in studies of children and adults, but data in pregnancy are sparse. In a cohort of mildly to moderately iodine-deficient pregnant women, this study aimed to explore whether serum Tg is a sensitive functional biomarker of iodine status and to examine longitudinal change in Tg with gestational age.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research