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The Impact of Noninvasive Follicular Variant of Papillary Thyroid Carcinoma on Rates of Malignancy for Fine-Needle Aspiration Diagnostic Categories
Author(s) -
Kyle C. Strickland,
Brooke E. Howitt,
Ellen Marqusee,
Erik K. Alexander,
Edmund S. Cibas,
Jeffrey F. Krane,
Justine A. Barletta
Publication year - 2015
Publication title -
thyroid
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.918
H-Index - 142
eISSN - 1557-9077
pISSN - 1050-7256
DOI - 10.1089/thy.2014.0612
Subject(s) - medicine , malignancy , fine needle aspiration , atypia , cytopathology , thyroid carcinoma , thyroid , pathology , radiology , carcinoma , lymphovascular invasion , biopsy , cancer , cytology , metastasis
Increased recognition of the indolent nature of noninvasive follicular variant of papillary thyroid carcinoma (NFVPTC) along with greater insight into the molecular alterations of these tumors has prompted endocrine pathologists to question whether these tumors warrant a diagnosis of carcinoma. However, a change in terminology would affect the rates of malignancy of fine-needle aspiration (FNA) diagnostic categories. Therefore, the aim of this study was to determine the percentage decrease in associated risk of malignancy for each FNA diagnostic category if NFVPTCs were no longer termed carcinomas.

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