Platelet-Rich Plasma for the Treatment of Tissue Infection: Preparation and Clinical Evaluation | Zendy

Wenhai Zhang | Zendy; Yue Guo | Zendy; Mitchell Kuss | Zendy; Wen Shi | Zendy; Amy L. Aldrich | Zendy; Jason Untrauer | Zendy; Tammy Kielian | Zendy; Bin Duan | Zendy

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Platelet-Rich Plasma for the Treatment of Tissue Infection: Preparation and Clinical Evaluation

Author(s) -

Wenhai Zhang,

Yue Guo,

Mitchell Kuss,

Wen Shi,

Amy L. Aldrich,

Jason Untrauer,

Tammy Kielian,

Bin Duan

Publication year - 2019

Publication title -

tissue engineering part b reviews

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.579

H-Index - 91

eISSN - 1937-3376

pISSN - 1937-3368

DOI - 10.1089/ten.teb.2018.0309

Subject(s) - platelet , medicine , platelet rich plasma , intensive care medicine , immunology

The clinical application of platelet-rich plasma (PRP) has been widely studied for its effects on trauma or injury repair/regeneration, however the antibacterial property of PRP has been overlooked. Increasing evidence suggests PRP as a good antibacterial agent and that it could help prevent/treat tissue infection. This review emphasizes the importance of PRP's antibacterial property and summarizes the preclinical and clinical findings regarding the application of PRP in the prevention and treatment of wound and bone infection. The use of biocompatible PRP may be advantageous for tissue infection treatment due to its inherent antibacterial and healing promoting properties.

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