The Bidirectional Interactions Between Inflammation and Coagulation in Fracture Hematoma | Zendy

Yaping Ma | Zendy; Yinghong Zhou | Zendy; Fujun Wu | Zendy; Wenjun Ji | Zendy; Jun Zhang | Zendy; Xin Wang | Zendy

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The Bidirectional Interactions Between Inflammation and Coagulation in Fracture Hematoma

Author(s) -

Yaping Ma,

Yinghong Zhou,

Fujun Wu,

Wenjun Ji,

Jun Zhang,

Xin Wang

Publication year - 2018

Publication title -

tissue engineering part b reviews

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.579

H-Index - 91

eISSN - 1937-3376

pISSN - 1937-3368

DOI - 10.1089/ten.teb.2018.0157

Subject(s) - hematoma , coagulation , medicine , inflammation , fracture (geology) , intensive care medicine , surgery , materials science , composite material

The review leads to better understanding of the interrelation between inflammation mediators and coagulation factors in the early fracture hematoma, and their influences on hematoma formation in the beginning of fracture healing. Furthermore, development of therapies aimed at simultaneous modulation of both coagulation factors and inflammation factors that affect hematoma structure, rather than specific factors, may be most promising.

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