Beyond Cartilage Repair: The Role of the Osteochondral Unit in Joint Health and Disease | Zendy

Sarah I. M. Lepage | Zendy; Naomi Robson | Zendy; Hillary Gilmore | Zendy; Ola S. Davis | Zendy; Allyssa Hooper | Zendy; Stephanie St. John | Zendy; Vashine Kamesan | Zendy; Paul Gelis | Zendy; Dia. Carvajal | Zendy; Mark Hurtig | Zendy; Thomas G. Koch | Zendy

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Beyond Cartilage Repair: The Role of the Osteochondral Unit in Joint Health and Disease

Author(s) -

Sarah I. M. Lepage,

Naomi Robson,

Hillary Gilmore,

Ola S. Davis,

Allyssa Hooper,

Stephanie St. John,

Vashine Kamesan,

Paul Gelis,

Dia. Carvajal,

Mark Hurtig,

Thomas G. Koch

Publication year - 2019

Publication title -

tissue engineering part b reviews

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.579

H-Index - 91

eISSN - 1937-3376

pISSN - 1937-3368

DOI - 10.1089/ten.teb.2018.0122

Subject(s) - multidisciplinary approach , cartilage , medicine , subchondral bone , articular cartilage , joint disease , disease , intensive care medicine , pathology , osteoarthritis , anatomy , alternative medicine , political science , law

In this comprehensive review, we are providing a holistic overview of osteochondral tissue development, disease, pain localization, as well as structural evaluation and current repair strategies. This review is intended to serve as a broad introduction to this multidisciplinary research area. It is a thorough examination of the biological aspects of the osteochondral unit from a tissue engineering perspective, highlighting the importance of the subchondral bone in chondral and osteochondral lesion repair and pain relief.

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