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Bacterial Burden in Critically Injured Ventilated Patients Does Not Correlate with Progression to Pneumonia
Author(s) -
Bradley M. Dennis,
Richard Betzold,
Daryl Patton,
Herbert A. Hopper,
Judith M. Jenkins,
Chris Fonnesbeck,
Wonder P. Drake,
Addison K. May
Publication year - 2018
Publication title -
surgical infections
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.773
H-Index - 60
eISSN - 1557-8674
pISSN - 1096-2964
DOI - 10.1089/sur.2017.199
Subject(s) - medicine , intensive care medicine , pneumonia , critically ill , ventilator associated pneumonia , mechanical ventilation , critical illness , intensive care unit
Ventilator-associated pneumonia (VAP) is common in critically injured patients. The pathogenesis of VAP is not completely understood. We hypothesized that mechanically ventilated trauma patients who develop pneumonia have a progressive increase in pathogen burden over the course of ventilation until a threshold for symptomatic pneumonia is reached, leading to clinical suspicion of VAP.

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