Pharmacokinetic Profile of Inhaled Submicron Particle Paclitaxel (NanoPac®) in a Rodent Model | Zendy

James Verco | Zendy; William F. Johnston | Zendy; Michael Baltezor | Zendy; Philip J. Kuehl | Zendy; Andrew P. Gigliotti | Zendy; Steven A. Belinsky | Zendy; Anita Lopez | Zendy; Ronald K. Wolff | Zendy; Lauren Hylle | Zendy; Gere S. diZerega | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Pharmacokinetic Profile of Inhaled Submicron Particle Paclitaxel (NanoPac^®) in a Rodent Model

Author(s) -

James Verco,

William F. Johnston,

Michael Baltezor,

Philip J. Kuehl,

Andrew P. Gigliotti,

Steven A. Belinsky,

Anita Lopez,

Ronald K. Wolff,

Lauren Hylle,

Gere S. diZerega

Publication year - 2018

Publication title -

journal of aerosol medicine and pulmonary drug delivery

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.678

H-Index - 68

eISSN - 1941-2703

pISSN - 1941-2711

DOI - 10.1089/jamp.2018.1467

Subject(s) - paclitaxel , pharmacokinetics , cmax , histopathology , lung , pharmacology , inhalation , toxicokinetics , toxicity , medicine , chemistry , pathology , chemotherapy , anesthesia

Inhaled chemotherapeutics may enhance pulmonary drug exposure to malignant lesions in the lung without substantially contributing to systemic toxicities. The pharmacokinetic profile of inhaled submicron particle paclitaxel (NanoPac ® ) in healthy rodent plasma and lung tissue is evaluated here to determine administration proof-of-principle.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research