Open AccessIn Vitro Determination of Respimat® Dose Delivery in Children: An Evaluation Based on Inhalation Flow Profiles and Mouth–Throat Models
Author(s) -
Deborah Bickmann,
Wolfgang Kamin,
Ashish Sharma,
Herbert Wachtel,
Petra Moroni-Zentgraf,
Stefan Zielen
Publication year - 2015
Publication title -
journal of aerosol medicine and pulmonary drug delivery
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.678
H-Index - 68
eISSN - 1941-2703
pISSN - 1941-2711
DOI - 10.1089/jamp.2014.1166
Subject(s) - inhalation , medicine , cystic fibrosis , nuclear medicine , lung , throat , anesthesia , surgery
Aerosol therapy in young children can be difficult. A realistic model based on handling studies and in vitro investigations can complement clinical deposition studies and be used to enable dose-to-the-lung (DTL) predictions.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom