Rapid Detection of the Three Celiac Disease Risk Genotypes HLA-DQ2.2, HLA-DQ2.5, and HLA-DQ8 by Multiplex Ligation-Dependent Probe Amplification | Zendy

Raymon Vijzelaar | Zendy; Ellen van der Zwan | Zendy; Adriaan van Gammeren | Zendy; Rizkat Yilmaz | Zendy; Alice Verheul | Zendy; Ingrid van Hoogstraten | Zendy; Ellen de Baar | Zendy; Lianne Schrauwen | Zendy; Wouter Kortlandt | Zendy

Open Access

Rapid Detection of the Three Celiac Disease Risk Genotypes HLA-DQ2.2, HLA-DQ2.5, and HLA-DQ8 by Multiplex Ligation-Dependent Probe Amplification

Author(s) -

Raymon Vijzelaar,

Ellen van der Zwan,

Adriaan van Gammeren,

Rizkat Yilmaz,

Alice Verheul,

Ingrid van Hoogstraten,

Ellen de Baar,

Lianne Schrauwen,

Wouter Kortlandt

Publication year - 2016

Publication title -

genetic testing and molecular biomarkers

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.405

H-Index - 47

eISSN - 1945-0265

pISSN - 1945-0257

DOI - 10.1089/gtmb.2015.0233

Subject(s) - multiplex ligation dependent probe amplification , genotyping , multiplex , human leukocyte antigen , genotype , multiplex polymerase chain reaction , biology , immunology , polymerase chain reaction , genetics , antigen , gene , exon

Genotyping of HLA-DQ2.2, HLA-DQ2.5, and HLA-DQ8 is important in celiac disease (CD). The absence of these three genotypes has a strong negative predictive value.

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