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Too Much Compromise in Today's CRISPR Pipelines
Author(s) -
Richard J. Fox
Publication year - 2019
Publication title -
the crispr journal
Language(s) - English
Resource type - Journals
eISSN - 2573-1602
pISSN - 2573-1599
DOI - 10.1089/crispr.2019.0015
Subject(s) - crispr , pace , computer science , scalability , compromise , variety (cybernetics) , multiplex , genome editing , set (abstract data type) , data science , artificial intelligence , bioinformatics , biology , database , programming language , geography , political science , biochemistry , geodesy , gene , law
CRISPR-based editing is a revolutionary tool for genome engineering and discovery. The pace of innovation in this young field is truly astonishing, and yet significant gaps remain in the set of capabilities offered. In particular, scalable (massively parallel and multiplex) editing is only available for a small variety of edit types, placing fundamental limits on the kinds of studies researchers can perform. Additional advancements are needed to realize the full potential of the technology.

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