Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis | Zendy

Rohit Chugh | Zendy; Vincent Olorunnisomo | Zendy; Evan Fowle | Zendy; Ippolito Modica | Zendy; Ira S. Meisels | Zendy; Mantu Gupta | Zendy

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Renal Papillary Necrosis Caused by Protein C Deficiency Leading to Recurrent Hydronephrosis

Author(s) -

Rohit Chugh,

Vincent Olorunnisomo,

Evan Fowle,

Ippolito Modica,

Ira S. Meisels,

Mantu Gupta

Publication year - 2016

Publication title -

journal of endourology case reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.123

H-Index - 1

ISSN - 2379-9889

DOI - 10.1089/cren.2016.0018

Subject(s) - hydronephrosis , medicine , renal papillary necrosis , kidney , necrosis , kidney disease , acute tubular necrosis , disease , acute kidney injury , pathology , urinary system

A patient with history of a solitary functioning kidney and protein C deficiency (PCD) presented with recurrent severe hydronephrosis causing acute kidney injury upon chronic kidney disease. Work-up with endoscopic evaluation revealed renal papillary necrosis (RPN) and sloughed renal papillae to be the true cause of the recurrent obstruction. Pathologic evaluation of the sloughed tissue confirmed the diagnosis of RPN. This is the first case reported in the literature illustrating the unique presentation of RPN in the setting of PCD.

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