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Dasotraline in Children with Attention-Deficit/Hyperactivity Disorder: A Six-Week, Placebo-Controlled, Fixed-Dose Trial
Author(s) -
Robert L. Findling,
Lenard A. Adler,
Thomas Spencer,
Robert Goldman,
Seth C. Hopkins,
Kenneth S. Koblan,
Justine Kent,
Jay Hsu,
Antony Loebel
Publication year - 2019
Publication title -
journal of child and adolescent psychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 84
eISSN - 1557-8992
pISSN - 1044-5463
DOI - 10.1089/cap.2018.0083
Subject(s) - placebo , discontinuation , attention deficit hyperactivity disorder , rating scale , clinical global impression , randomized controlled trial , adverse effect , medicine , clinical endpoint , atomoxetine hydrochloride , psychology , pediatrics , psychiatry , methylphenidate , atomoxetine , developmental psychology , alternative medicine , pathology
Dasotraline is a potent inhibitor of presynaptic dopamine and norepinephrine reuptake with a pharmacokinetic profile characterized by slow absorption and a long elimination half-life. The aim of this study was to evaluate the efficacy and safety of dasotraline in children with attention-deficit/hyperactivity disorder (ADHD).

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