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Randomized, Double-Blind, Placebo-Controlled Trial Demonstrates the Efficacy and Safety of Oral Aripiprazole for the Treatment of Tourette's Disorder in Children and Adolescents
Author(s) -
Floyd R. Sallee,
Eva Kohegyi,
Joan Zhao,
Robert D. McQuade,
Kevin Cox,
Raymond Sanchez,
Alet van Beek,
Margaretta Nyilas,
William H. Carson,
Roger Kurlan
Publication year - 2017
Publication title -
journal of child and adolescent psychopharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.935
H-Index - 84
eISSN - 1557-8992
pISSN - 1044-5463
DOI - 10.1089/cap.2016.0026
Subject(s) - aripiprazole , placebo , tourette syndrome , randomized controlled trial , medicine , clinical endpoint , population , tics , randomization , adverse effect , placebo controlled study , psychology , psychiatry , pediatrics , double blind , schizophrenia (object oriented programming) , alternative medicine , environmental health , pathology
Aripiprazole modulates dopaminergic and serotonergic pathways that may play a role in the pathogenesis of Tourette's disorder (TD). This trial evaluated the efficacy and safety of oral aripiprazole in the suppression of tics in children and adolescents with TD.

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