Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group | Zendy

Fay Betsou | Zendy; Alexandre Bulla | Zendy; Sang Yun Cho | Zendy; Judith A. Clements | Zendy; Rodrigo Chuaqui | Zendy; Domenico Coppola | Zendy; Yvonne De Souza | Zendy; Annemieke De Wilde | Zendy; William E. Grizzle | Zendy; Fiorella Guadagni | Zendy; Elaine W. Gunter | Zendy; Stacey Heil | Zendy; Verity S. Hodgkinson | Zendy; Joseph Kessler | Zendy; Michael Kiehntopf | Zendy; Hee Sung Kim | Zendy; Iren Koppandi | Zendy; Katheryn Shea | Zendy; Rajeev Kumar Singh | Zendy; Marc Sobel | Zendy; Stella Somiari | Zendy; Demetri D. Spyropoulos | Zendy; Mars Stone | Zendy; Gunnel Tybring | Zendy; Klara ValyiNagy | Zendy; Gert Van den Eynden | Zendy; Lalita Wadhwa | Zendy

Open Access

Assays for Qualification and Quality Stratification of Clinical Biospecimens Used in Research: A Technical Report from the ISBER Biospecimen Science Working Group

Author(s) -

Fay Betsou,

Alexandre Bulla,

Sang Yun Cho,

Judith A. Clements,

Rodrigo Chuaqui,

Domenico Coppola,

Yvonne De Souza,

Annemieke De Wilde,

William E. Grizzle,

Fiorella Guadagni,

Elaine W. Gunter,

Stacey Heil,

Verity S. Hodgkinson,

Joseph Kessler,

Michael Kiehntopf,

Hee Sung Kim,

Iren Koppandi,

Katheryn Shea,

Rajeev Kumar Singh,

Marc Sobel,

Stella Somiari,

Demetri D. Spyropoulos,

Mars Stone,

Gunnel Tybring,

Klara ValyiNagy,

Gert Van den Eynden,

Lalita Wadhwa

Publication year - 2016

Publication title -

biopreservation and biobanking

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.545

H-Index - 34

eISSN - 1947-5535

pISSN - 1947-5543

DOI - 10.1089/bio.2016.0018

Subject(s) - quality (philosophy) , risk stratification , biorepository , medical physics , computer science , computational biology , medicine , biobank , bioinformatics , biology , physics , quantum mechanics

This technical report presents quality control (QC) assays that can be performed in order to qualify clinical biospecimens that have been biobanked for use in research. Some QC assays are specific to a disease area. Some QC assays are specific to a particular downstream analytical platform. When such a qualification is not possible, QC assays are presented that can be performed to stratify clinical biospecimens according to their biomolecular quality.

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