Method Validation for Preparing Serum and Plasma Samples from Human Blood for Downstream Proteomic, Metabolomic, and Circulating Nucleic Acid-Based Applications | Zendy

Wim Ammerlaan | Zendy; JeanPierre Trezzi | Zendy; Pierre Lescuyer | Zendy; Conny Mathay | Zendy; Karsten Hiller | Zendy; Fay Betsou | Zendy

Open Access

Method Validation for Preparing Serum and Plasma Samples from Human Blood for Downstream Proteomic, Metabolomic, and Circulating Nucleic Acid-Based Applications

Author(s) -

Wim Ammerlaan,

JeanPierre Trezzi,

Pierre Lescuyer,

Conny Mathay,

Karsten Hiller,

Fay Betsou

Publication year - 2014

Publication title -

biopreservation and biobanking

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.545

H-Index - 34

eISSN - 1947-5535

pISSN - 1947-5543

DOI - 10.1089/bio.2014.0003

Subject(s) - centrifugation , reproducibility , chromatography , metabolomics , chemistry , microparticle , context (archaeology) , biology , paleontology , astrobiology

Formal method validation for biospecimen processing in the context of accreditation in laboratories and biobanks is lacking. Serum and plasma processing protocols were validated for fitness-for-purpose in terms of key downstream endpoints, and this article demonstrates methodology for biospecimen processing method validation.

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