The Broad-Spectrum Antimicrobial Potential of [Mn(CO)4(S2CNMe(CH2CO2H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation, Transcriptomic and Statistical Analyses, and Membrane Polarization | Zendy

Lauren K. Wareham | Zendy; Samantha McLean | Zendy; Ronald Begg | Zendy; Namrata Rana | Zendy; Salar Ibrahim Ali | Zendy; John J. Kendall | Zendy; Guido Sanguinetti | Zendy; Brian E. Mann | Zendy; Robert K. Poole | Zendy

Open Access

The Broad-Spectrum Antimicrobial Potential of [Mn(CO)₄(S₂CNMe(CH₂CO₂H))], a Water-Soluble CO-Releasing Molecule (CORM-401): Intracellular Accumulation, Transcriptomic and Statistical Analyses, and Membrane Polarization

Author(s) -

Lauren K. Wareham,

Samantha McLean,

Ronald Begg,

Namrata Rana,

Salar Ibrahim Ali,

John J. Kendall,

Guido Sanguinetti,

Brian E. Mann,

Robert K. Poole

Publication year - 2017

Publication title -

antioxidants and redox signaling

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.277

H-Index - 190

eISSN - 1557-7716

pISSN - 1523-0864

DOI - 10.1089/ars.2017.7239

Subject(s) - biochemistry , antimicrobial , chemistry , intracellular , biology , biophysics , microbiology and biotechnology

Carbon monoxide (CO)-releasing molecules (CORMs) are candidates for animal and antimicrobial therapeutics. We aimed to probe the antimicrobial potential of a novel manganese CORM.

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