Genome-Scale Modeling of NADPH-Driven β-Lapachone Sensitization in Head and Neck Squamous Cell Carcinoma | Zendy

Joshua E. Lewis | Zendy; Francesco Costantini | Zendy; Jade Mims | Zendy; Xiaofei Chen | Zendy; Cristina M. Furdui | Zendy; David A. Boothman | Zendy; Melissa L. Kemp | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Genome-Scale Modeling of NADPH-Driven β-Lapachone Sensitization in Head and Neck Squamous Cell Carcinoma

Author(s) -

Joshua E. Lewis,

Francesco Costantini,

Jade Mims,

Xiaofei Chen,

Cristina M. Furdui,

David A. Boothman,

Melissa L. Kemp

Publication year - 2017

Publication title -

antioxidants and redox signaling

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.277

H-Index - 190

eISSN - 1557-7716

pISSN - 1523-0864

DOI - 10.1089/ars.2017.7048

Subject(s) - sensitization , head and neck squamous cell carcinoma , head and neck cancer , head and neck , genome , basal cell , scale (ratio) , cancer research , medicine , biology , gene , genetics , cancer , immunology , surgery , physics , quantum mechanics

The purpose of this study was to investigate differential nicotinamide adenine dinucleotide phosphate, reduced (NADPH) production between radiation-sensitive and -resistant head and neck squamous cell carcinoma (HNSCC) cell lines and whether these differences are predictive of sensitivity to the chemotherapeutic β-lapachone.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research