Modulation of T Cell Activation in Obesity | Zendy

Stéphanie O. Morin | Zendy; Marjorie Poggi | Zendy; MarieChristine Alessi | Zendy; JeanFrançois Landrier | Zendy; Jacques A. Nunès | Zendy

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Modulation of T Cell Activation in Obesity

Author(s) -

Stéphanie O. Morin,

Marjorie Poggi,

MarieChristine Alessi,

JeanFrançois Landrier,

Jacques A. Nunès

Publication year - 2016

Publication title -

antioxidants and redox signaling

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.277

H-Index - 190

eISSN - 1557-7716

pISSN - 1523-0864

DOI - 10.1089/ars.2016.6746

Subject(s) - t cell , cd28 , cd154 , inflammation , microbiology and biotechnology , immune system , adipose tissue , antigen presenting cell , zap70 , biology , chemistry , cd40 , immunology , cytotoxic t cell , endocrinology , biochemistry , in vitro

Immune T cells are present in adipose tissues (AT), and the stoichiometry of the different T cell subsets is altered during diet-induced obesity (DIO). T cells contribute to the early steps of AT inflammation during DIO. Recent Advances: Many factors could potentially be responsible for this altered pro-inflammatory versus anti-inflammatory T cell balance.

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