Functional MicroRNA Library Screening Identifies the HypoxaMiR MiR-24 as a Potent Regulator of Smooth Muscle Cell Proliferation and Vascularization | Zendy

Jan Fiedler | Zendy; Andrea Stöhr | Zendy; Shashi Kumar Gupta | Zendy; Dorothee Hartmann | Zendy; Angelika Holzmann | Zendy; Annette Just | Zendy; Arne Hansen | Zendy; Denise HilfikerKleiner | Zendy; Thomas Eschenhagen | Zendy; Thomas Thum | Zendy

Open Access

Functional MicroRNA Library Screening Identifies the HypoxaMiR MiR-24 as a Potent Regulator of Smooth Muscle Cell Proliferation and Vascularization

Author(s) -

Jan Fiedler,

Andrea Stöhr,

Shashi Kumar Gupta,

Dorothee Hartmann,

Angelika Holzmann,

Annette Just,

Arne Hansen,

Denise HilfikerKleiner,

Thomas Eschenhagen,

Thomas Thum

Publication year - 2013

Publication title -

antioxidants and redox signaling

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.277

H-Index - 190

eISSN - 1557-7716

pISSN - 1523-0864

DOI - 10.1089/ars.2013.5418

Subject(s) - biology , microrna , microbiology and biotechnology , regulator , cell growth , autophagy , phenotype , regulation of gene expression , gene expression , gene , apoptosis , cancer research , genetics

Smooth muscle cells (SMCs) are key components within the vasculature. Dependent on the stimulus, SMC can either be in a proliferative (synthetic) or differentiated state. Alterations of SMC phenotype also appear in several disease settings, further contributing to disease progression.

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