Younger Age Predicts Failure to Achieve Viral Suppression and Virologic Rebound Among HIV-1-Infected Persons in Serodiscordant Partnerships | Zendy

Andrew Mujugira | Zendy; Connie Celum | Zendy; Jordan W. Tappero | Zendy; Allan Ronald | Zendy; Nelly Mugo | Zendy; Jared M. Baeten | Zendy

Open Access

Younger Age Predicts Failure to Achieve Viral Suppression and Virologic Rebound Among HIV-1-Infected Persons in Serodiscordant Partnerships

Author(s) -

Andrew Mujugira,

Connie Celum,

Jordan W. Tappero,

Allan Ronald,

Nelly Mugo,

Jared M. Baeten

Publication year - 2015

Publication title -

aids research and human retroviruses

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.993

H-Index - 92

eISSN - 1931-8405

pISSN - 0889-2229

DOI - 10.1089/aid.2015.0296

Subject(s) - serodiscordant , viral load , hazard ratio , proportional hazards model , medicine , human immunodeficiency virus (hiv) , immunology , young adult , prospective cohort study , antiretroviral therapy , confidence interval

Antiretroviral therapy (ART) markedly reduces the risk of HIV-1 transmission in serodiscordant partnerships. We previously found that younger age and higher CD4 counts were associated with delayed initiation of ART by HIV-1-infected partners in serodiscordant partnerships. Among those initiating ART, we sought to explore whether those same factors were associated with failure to achieve viral suppression.

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