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The incidence of ventilator-associated pneumonia (VAP) due to multidrug-resistant (MDR) organisms is increasing. Intravenous (IV) colistin or aerosolized (AS) plus IV colistin have been recently used to treat these life-threatening infections. The purpose of this study was to compare the efficacy and safety of AS plus IV colistin versus IV colistin alone for patients with MDR VAP due to gram-negative bacteria.

clinical infectious diseases/clinical infectious diseases (online. university of chicago. press)

Aerosolized plus Intravenous Colistin versus Intravenous Colistin Alone for the Treatment of Ventilator‐Associated Pneumonia: A Matched Case‐Control Study