Open AccessStaphylococcal Superantigens Cause Lethal Pulmonary Disease in Rabbits
Author(s) -
Kristi L. Strandberg,
Jessica H. Rotschafer,
Sara M. Vetter,
Rebecca A. Buonpane,
David M. Kranz,
Patrick M. Schlievert
Publication year - 2010
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/657156
Subject(s) - superantigen , medicine , immunology , disease , pulmonary disease , pathology , immune system , t cell
The Centers for Disease Control and Prevention (CDC) and others reported that methicillin-resistant S. aureus (MRSA) are significant causes of serious human infections, including pulmonary illnesses. We investigated the role played by superantigens in lung-associated lethal illness in rabbits.