Artemisinin Resistance in Cambodia: A Clinical Trial Designed to Address an Emerging Problem in Southeast Asia | Zendy

Harald Noedl | Zendy; Youry Se | Zendy; Sabaithip Sriwichai | Zendy; Kurt E. Schaecher | Zendy; Paktiya TejaIsavadharm | Zendy; Bryan Smith | Zendy; Wiriya Rutvisuttinunt | Zendy; Delia Bethell | Zendy; Sittidech Surasri | Zendy; Mark M. Fukuda | Zendy; Duong Socheat | Zendy; Lon Chan Thap | Zendy

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Artemisinin Resistance in Cambodia: A Clinical Trial Designed to Address an Emerging Problem in Southeast Asia

Author(s) -

Harald Noedl,

Youry Se,

Sabaithip Sriwichai,

Kurt E. Schaecher,

Paktiya TejaIsavadharm,

Bryan Smith,

Wiriya Rutvisuttinunt,

Delia Bethell,

Sittidech Surasri,

Mark M. Fukuda,

Duong Socheat,

Lon Chan Thap

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/657120

Subject(s) - medicine , artemisinin , southeast asia , resistance (ecology) , clinical trial , traditional medicine , intensive care medicine , malaria , ancient history , immunology , plasmodium falciparum , history , ecology , biology

Increasing rates of failure of artemisinin-based combination therapy have highlighted the possibility of emerging artemisinin resistance along the Thai-Cambodian border. We used an integrated in vivo-in vitro approach to assess the presence of artemisinin resistance in western Cambodia. This article provides additional data from a clinical trial that has been published in The New England Journal of Medicine.

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