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HIV Type 2 in New York City, 2000–2008
Author(s) -
Lucia V. Torian,
Joanna Eavey,
Amado Punsalang,
Robert E. Pirillo,
Lisa A. Forgione,
Scott A. Kent,
William R. Oleszko
Publication year - 2010
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/657117
Subject(s) - medicine , immunosuppression , human immunodeficiency virus (hiv) , immunology , virology , serology , viral load , antibody
Antibody cross-reactivity complicates differential diagnosis of human immunodeficiency virus (HIV) type 2 (HIV-2) using standard serologic screening and confirmatory tests for HIV. HIV type 1 (HIV-1) viral load testing does not detect HIV-2. Although HIV-2 is, in general, less pathogenic than HIV-1, it can lead to immunosuppression and clinical AIDS, and there are important differences in the selection of antiretroviral therapy for HIV-2-related immunosuppression that make it imperative to differentiate between the 2 viruses. The New York City Department of Health (New York, NY) seeks to facilitate accurate diagnosis and surveillance of HIV-2 infection in the city.

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