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Initiation of antiretroviral therapy (ART) in human immunodeficiency virus patients with treated or unrecognized Mycobacterium tuberculosis infection may result in tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) or ART-associated tuberculosis (ART-TB), respectively. Both conditions appear to be immune restoration disease but their immunopathogenesis is not completely understood.

the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases

Mediators of Innate and Adaptive Immune Responses Differentially Affect Immune Restoration Disease Associated with<i>Mycobacterium tuberculosis</i>in HIV Patients Beginning Antiretroviral Therapy

Mediators of Innate and Adaptive Immune Responses Differentially Affect Immune Restoration Disease Associated withMycobacterium tuberculosisin HIV Patients Beginning Antiretroviral Therapy