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Colistin‐Tobramycin Combinations Are Superior to Monotherapy Concerning the Killing of BiofilmPseudomonas aeruginosa
Author(s) -
Gloria Herrmann,
Liang Yang,
Hong Wu,
Zhijun Song,
Hengzhuang Wang,
Niels Høiby,
Martina Ulrich,
Søren Molin,
Joachim Riethmüller,
Gerd Döring
Publication year - 2010
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/656788
Subject(s) - tobramycin , colistin , pseudomonas aeruginosa , biofilm , cystic fibrosis , antibiotics , microbiology and biotechnology , medicine , aminoglycoside , gentamicin , biology , bacteria , genetics
Antibiotic combination therapy might be more efficient than single antibiotics to combat Pseudomonas aeruginosa biofilms in the airways of patients with cystic fibrosis. We tested the ability of colistin sulphate-tobramycin combinations and single antibiotics to kill P. aeruginosa biofilms.

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