Transcriptome Analysis Indicates an Enhanced Activation of Adaptive and Innate Immunity byChlamydia‐Infected Murine Epithelial Cells Treated with Interferon γ
Author(s) -
Katalin Burián,
Valéria Endrész,
J Deák,
Zsolt Kormányos,
Attila Pál,
David E. Nelson,
Dezső P. Virók
Publication year - 2010
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/656526
Subject(s) - biology , chlamydia trachomatis , innate immune system , transcriptome , chemokine , chlamydia , interferon , cytokine , cxcl10 , tlr9 , ccl22 , gene expression , immunology , microbiology and biotechnology , gene , immune system , genetics , dna methylation
Interferon γ (IFN‐γ) is the major cytokine involved in the elimination of Chlamydia infection. Despite its importance, the combined effect of Chlamydia infection and IFN‐γ on the gene expression of murine epithelial cells has only partially been described.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom