Toll‐Like Receptor 4 Polymorphism and Its Association with Symptomatic Neurocysticercosis
Author(s) -
Avantika Verma,
Kashi Nath Prasad,
Rakesh Gupta,
Aloukick Kumar Singh,
Kishan Kumar Nyati,
Arshi Rizwan,
Chandra M. Pandey,
Vimal Kumar Paliwal
Publication year - 2010
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/656395
Subject(s) - asymptomatic , neurocysticercosis , tlr4 , immunology , medicine , pathogenesis , gastroenterology , immune system , allele , biology , pathology , gene , genetics
Symptoms and signs of neurocysticercosis (NCC) are nonspecific and depend upon several factors, including the host immune response to the parasite. Toll-like receptors (TLRs) play an important role in innate immunity. Susceptibility of humans to NCC in relation to TLR polymorphism is unknown. The present study examines TLR4 polymorphism in human NCC and its role in symptomatic disease.
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