Multicity Outbreak of Linezolid‐ResistantStaphylococcus epidermidisAssociated with Clonal Spread of acfr‐Containing Strain
Author(s) -
Hector Bonilla,
Michael D. Huband,
Joan Seidel,
Helen Schmidt,
Marykay Lescoe,
Sandra P. McCurdy,
M. Megan Lemmon,
LORI BRENNAN,
Amelia TaitKamradt,
Laura Puzniak,
John P. Quinn
Publication year - 2010
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/656281
Subject(s) - linezolid , staphylococcus epidermidis , outbreak , medicine , clone (java method) , microbiology and biotechnology , 23s ribosomal rna , staphylococcus aureus , strain (injury) , virology , biology , gene , bacteria , genetics , rna , vancomycin , ribosome
We report a multicity outbreak of cfr-containing linezolid-resistant Staphylococcus epidermidis in Ohio. Thirty-nine isolates were obtained from 2 hospitals. Two clones with different mechanisms of linezolid resistance were circulating in hospital A. One of these contained the cfr gene, and the other a ribosomal mutation. The clone containing cfr was identical in both hospitals.
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