Adaptive Differentiation ofPlasmodium falciparumPopulations Inferred from Single‐Nucleotide Polymorphisms (SNPs) Conferring Drug Resistance and from Neutral SNPs | Zendy

Oumou MaïgaAscofaré | Zendy; Jacques Le Bras | Zendy; Rabia Mazmouz | Zendy; Emmanuelle Renard | Zendy; Sarah Falcão | Zendy; Emeline Broussier | Zendy; Dorina Bustos | Zendy; Milijaona Randrianarivelojosia | Zendy; Sabah A. Omar | Zendy; Agnès Aubouy | Zendy; JeanFrançois Lepère | Zendy; Vély JeanFrançois | Zendy; Abdoulaye Djimdé | Zendy; Jérôme Clain | Zendy

Open Access

Adaptive Differentiation ofPlasmodium falciparumPopulations Inferred from Single‐Nucleotide Polymorphisms (SNPs) Conferring Drug Resistance and from Neutral SNPs

Author(s) -

Oumou MaïgaAscofaré,

Jacques Le Bras,

Rabia Mazmouz,

Emmanuelle Renard,

Sarah Falcão,

Emeline Broussier,

Dorina Bustos,

Milijaona Randrianarivelojosia,

Sabah A. Omar,

Agnès Aubouy,

JeanFrançois Lepère,

Vély JeanFrançois,

Abdoulaye Djimdé,

Jérôme Clain

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/656142

Subject(s) - single nucleotide polymorphism , biology , plasmodium falciparum , genetics , malaria , context (archaeology) , allele , allele frequency , drug resistance , gene , genotype , immunology , paleontology

Theoretical and experimental data support the geographic differentiation strategy as a valuable tool for detecting loci under selection. In the context of Plasmodium falciparum malaria, few populations have been studied, with limited genomic coverage.

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