Genetic and Household Determinants of Predisposition to Human Hookworm Infection in a Brazilian Community | Zendy

Rupert J. Quinnell | Zendy; Rachel L. Pullan | Zendy; Lutz P. Breitling | Zendy; Stefan Michael Geiger | Zendy; Bonnie Cundill | Zendy; Rodrigo CorrêaOliveira | Zendy; Simon Brooker | Zendy; Jeffrey M. Bethony | Zendy

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Genetic and Household Determinants of Predisposition to Human Hookworm Infection in a Brazilian Community

Author(s) -

Rupert J. Quinnell,

Rachel L. Pullan,

Lutz P. Breitling,

Stefan Michael Geiger,

Bonnie Cundill,

Rodrigo CorrêaOliveira,

Simon Brooker,

Jeffrey M. Bethony

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/655813

Subject(s) - heritability , genetic predisposition , biology , necator americanus , genetic correlation , hookworm infection , genetic variability , genetic variation , genetics , immunology , helminths , genotype , gene , ascaris lumbricoides

Predisposition to heavy or light human hookworm infection is consistently reported in treatment-reinfection studies. A significant role for host genetics in determining hookworm infection intensity has also been shown, but the relationship between host genetics and predisposition has not been investigated.

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