Association of Profoundly Impaired Immune Competence in H1N1v‐Infected Patients with a Severe or Fatal Clinical Course | Zendy

Chiara Agrati | Zendy; Cristiana Gioia | Zendy; Eleonora Lalle | Zendy; Eleonora Cimini | Zendy; Concetta Castilletti | Zendy; Orlando Armignacco | Zendy; F. Lauria | Zendy; Federica Ferraro | Zendy; Mario Antonini | Zendy; Giuseppe Ippolito | Zendy; Maria Rosaria Capobianchi | Zendy; Federico Martini | Zendy

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Association of Profoundly Impaired Immune Competence in H1N1v‐Infected Patients with a Severe or Fatal Clinical Course

Author(s) -

Chiara Agrati,

Cristiana Gioia,

Eleonora Lalle,

Eleonora Cimini,

Concetta Castilletti,

Orlando Armignacco,

F. Lauria,

Federica Ferraro,

Mario Antonini,

Giuseppe Ippolito,

Maria Rosaria Capobianchi,

Federico Martini

Publication year - 2010

Publication title -

the journal of infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.69

H-Index - 252

eISSN - 1537-6613

pISSN - 0022-1899

DOI - 10.1086/655469

Subject(s) - pneumonia , viral pneumonia , immune system , immunology , respiratory failure , pandemic , medicine , intensive care medicine , covid-19 , disease , infectious disease (medical specialty)

Pandemic A/H1N1v influenza is characterized by a mild clinical course. However, a small subset of patients develops a rapidly progressive course caused by primary viral pneumonia or secondary bacterial infections that, in many cases, lead to death due to respiratory failure. The aim of the present study was to analyze the involvement of the immune response in the clinical presentation of H1N1v influenza.

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