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Interhuman Transmission as a Potential Key Parameter for Geographical Variation in the Prevalence ofPneumocystis jiroveciiDihydropteroate Synthase Mutations
Author(s) -
Philippe M. Hauser,
Aimable Nahimana,
Patrick Taffé,
Rainer Weber,
P Francioli,
Jacques Billé,
Méja Rabodonirina
Publication year - 2010
Publication title -
clinical infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.44
H-Index - 336
eISSN - 1537-6591
pISSN - 1058-4838
DOI - 10.1086/655145
Subject(s) - dihydropteroate synthase , dhps , pneumocystis jirovecii , medicine , genotype , transmission (telecommunications) , pneumocystis pneumonia , pneumonia , immunology , genetics , biology , gene , pyrimethamine , plasmodium falciparum , engineering , malaria , electrical engineering
Pneumocystis jirovecii dihydropteroate synthase (DHPS) mutations are associated with failure of prophylaxis with sulfa drugs. This retrospective study sought to better understand the geographical variation in the prevalence of these mutations.

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