Prolonged Infectiousness of Tuberculosis Patients in a Directly Observed Therapy Short‐Course Program with Standardized Therapy | Zendy

Sean Fitzwater | Zendy; Luz Caviedes | Zendy; Robert H. Gilman | Zendy; Jorge Coronel | Zendy; Doris LaChira | Zendy; Cayo Salazar | Zendy; Juan Carlos Saravia | Zendy; Krishna P. Reddy | Zendy; Jon S. Friedland | Zendy; David Moore | Zendy

Open Access

Prolonged Infectiousness of Tuberculosis Patients in a Directly Observed Therapy Short‐Course Program with Standardized Therapy

Author(s) -

Sean Fitzwater,

Luz Caviedes,

Robert H. Gilman,

Jorge Coronel,

Doris LaChira,

Cayo Salazar,

Juan Carlos Saravia,

Krishna P. Reddy,

Jon S. Friedland,

David Moore

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/655127

Subject(s) - medicine , tuberculosis , culture conversion , directly observed therapy , mycobacterium tuberculosis , drug resistance , surgery , pathology , sputum , microbiology and biotechnology , biology

Effective tuberculosis control is compromised by a lack of clarity about the timeframe of viable Mycobacterium tuberculosis shedding after treatment initiation under programmatic conditions. This study quantifies time to conversion from smear and culture positivity to negativity in unselected tuberculosis patients receiving standardized therapy in a directly observed therapy short-course (DOTS) program.

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