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Age prevalence curves for areas in which schistosomiasis is endemic suggest that humans develop partial immunity to reinfection beginning in early adolescence. We conducted a 2-year longitudinal study to determine whether children infected with Schistosoma mansoni develop protection-related immune responses after treatment with praziquantel and whether the development of these immune responses is accelerated by frequent treatment after reinfection.

the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases

Increases in Levels of Schistosome‐Specific Immunoglobulin E and CD23<sup>+</sup>B Cells in a Cohort of Kenyan Children Undergoing Repeated Treatment and Reinfection with<i>Schistosoma mansoni</i>

Increases in Levels of Schistosome‐Specific Immunoglobulin E and CD23+B Cells in a Cohort of Kenyan Children Undergoing Repeated Treatment and Reinfection withSchistosoma mansoni

Increases in Levels of Schistosome‐Specific Immunoglobulin E and CD23⁺B Cells in a Cohort of Kenyan Children Undergoing Repeated Treatment and Reinfection withSchistosoma mansoni