Comparison of 2 Different Regimens for Reactogenicity, Safety, and Immunogenicity of the Live Attenuated Oral Rotavirus Vaccine RIX4414 Coadministered with Oral Polio Vaccine in South African Infants
Author(s) -
A. Duncan Steele,
J. Reynders,
F. Scholtz,
P.K. Bos,
M. C. de Beer,
John Tumbo,
C.F. van der Merwe,
A. Delem,
Béatrice De Vos
Publication year - 2010
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/653550
Subject(s) - reactogenicity , medicine , seroconversion , immunogenicity , rotavirus vaccine , placebo , poliomyelitis , vaccination , regimen , poliovirus , rotavirus , immunology , virology , antibody , virus , alternative medicine , pathology
A phase II, randomized, double-blind, placebo-controlled study was conducted in South Africa during 2003-2004 to evaluate the safety, reactogenicity, and immunogenicity of 2 regimens of the live attenuated oral human rotavirus vaccine RIX4414 when coadministered with the Expanded Program on Immunization childhood vaccines, including oral polio vaccine.
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