High Prevalence of Macrolide Resistance inMycoplasma pneumoniaeIsolates from Adult and Adolescent Patients with Respiratory Tract Infection in China | Zendy

Bin Cao | Zendy; Chunjiang Zhao | Zendy; Yudong Yin | Zendy; Fei Zhao | Zendy; ShuFan Song | Zendy; Lu Bai | Zendy; Jianzhong Zhang | Zendy; Yingmei Liu | Zendy; YuYu Zhang | Zendy; Hui Wang | Zendy; Chen Wang | Zendy

Open Access

High Prevalence of Macrolide Resistance inMycoplasma pneumoniaeIsolates from Adult and Adolescent Patients with Respiratory Tract Infection in China

Author(s) -

Bin Cao,

Chunjiang Zhao,

Yudong Yin,

Fei Zhao,

ShuFan Song,

Lu Bai,

Jianzhong Zhang,

Yingmei Liu,

YuYu Zhang,

Hui Wang,

Chen Wang

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/653535

Subject(s) - mycoplasma pneumoniae , medicine , 23s ribosomal rna , respiratory tract , respiratory tract infections , mycoplasma , microbiology and biotechnology , macrolide antibiotics , virology , drug resistance , pneumonia , antibiotics , respiratory system , erythromycin , biology , gene , rna , ribosome , biochemistry

The resistance rate of 67 Mycoplasma pneumoniae isolates from 356 ambulatory adult patients with respiratory tract infection was 69% (46 of 67). All 46 macrolide-resistant strains harbored point mutations in the 23S ribosomal RNA gene. Patients infected with macrolide-resistant M. pneumoniae required significantly longer durations of antibiotic therapy and had longer time to resolution of fever.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research