Possible Mitochondrial Dysfunction and Its Association with Antiretroviral Therapy Use in Children Perinatally Infected with HIV
Author(s) -
Marilyn J. Crain,
Miriam C. Chernoff,
James M. Oleske,
Susan B. Brogly,
Kathleen Malee,
Peggy R. Borum,
William A. Meyer,
Wendy Mitchell,
Jack Moye,
Heather Ford-Chatterton,
Russell B. Van Dyke,
George R. Seage
Publication year - 2010
Publication title -
the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/653497
Subject(s) - antiretroviral therapy , human immunodeficiency virus (hiv) , medicine , mitochondrial toxicity , immunology , virology , incidence (geometry) , lentivirus , viral disease , viral load , physics , optics
Mitochondrial dysfunction has been associated with both human immunodeficiency virus (HIV) infection and exposure to antiretroviral therapy. Mitochondrial dysfunction has not been widely studied in HIV-infected children. We estimated the incidence of clinically defined mitochondrial dysfunction among children with perinatal HIV infection.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom