Open AccessSin Nombre Virus–Specific Immunoglobulin M and G Kinetics in Hantavirus Pulmonary Syndrome and the Role Played by Serologic Responses in Predicting Disease Outcome
Author(s) -
Adam MacNeil,
James A. Comer,
Thomas G. Ksiazek,
Pierre E. Rollin
Publication year - 2010
Publication title -
the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.69
H-Index - 252
eISSN - 1537-6613
pISSN - 0022-1899
DOI - 10.1086/653482
Subject(s) - serology , antibody , immunology , titer , immunoglobulin g , hantavirus , immunoglobulin m , biology , virus , hantavirus infection , virology , medicine
Sin Nombre virus (SNV) is the primary cause of hantavirus pulmonary syndrome (HPS) in the United States. Although other studies have demonstrated a possible association between neutralizing antibody titers and the severity of HPS, the exact nature of serologic responses and their association with outcomes have not been fully characterized.