Instantaneous Inhibitory Potential Is Similar to Inhibitory Quotient at Predicting HIV‐1 Response to Antiretroviral Therapy | Zendy

Timothy J. Henrich | Zendy; Heather J. Ribaudo | Zendy; Daniel R. Kuritzkes | Zendy

Open Access

Instantaneous Inhibitory Potential Is Similar to Inhibitory Quotient at Predicting HIV‐1 Response to Antiretroviral Therapy

Author(s) -

Timothy J. Henrich,

Heather J. Ribaudo,

Daniel R. Kuritzkes

Publication year - 2010

Publication title -

clinical infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.44

H-Index - 336

eISSN - 1537-6591

pISSN - 1058-4838

DOI - 10.1086/653430

Subject(s) - spearman's rank correlation coefficient , rank correlation , medicine , correlation , quotient , linear regression , viral load , human immunodeficiency virus (hiv) , gastroenterology , immunology , statistics , mathematics , geometry , pure mathematics

The instantaneous inhibitory potential (IIP), a measure of antiviral activity that incorporates the slope of the dose-response curve, has been proposed as a better predictor of clinical efficacy than the inhibitory quotient (IQ). However, there are no quantitative analyses supporting this hypothesis.

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